Fibromyalgia and Neurotransmission

Neurotransmission is the method by which nerves “speak” to each other so impulses can be sent from one part of your body to the brain and back. For example, when you touch a hot plate by accident, it doesn’t take long before you quickly let go of the plate. The reason you let go quickly is because of neurotransmission. Certain types of neurons or nerves (called afferents) bring information to the central nervous system where the information is processed and then signals are transferred back to the target site (such as your hand touching the hot plate) by different nerves (called efferents) telling you to immediately let go of that hot object.

It’s like the flow of traffic into a city during rush hour. People work all day and then drive in the opposite direction on their way home (afferents in the morning going in the city or “brain” and efferents in the evening bringing new information home). This “give and take” process of information coming in, being processed and going out helps coordinate our bodily functions. This allows us to constantly adapt to surrounding changes in temperature, stress, noise, and so on.

Each neuron has as many as 1500 connections from other neurons, but they don’t actually touch one another. Rather, there are “synapses” where nerve impulses stimulate the release of calcium and neurotransmitters, which either inhibit or excite another neuron and each neuron may be connected to many other neurons. If the total excitatory stimuli are greater than the inhibitory stimuli, that neuron will “fire” and create a new connection resulting in an action (like dropping the hot plate).

Okay, sorry for the enthusiastic description and details of neurotransmission. More importantly, how does all this relate to fibromyalgia? A new study (published May 14, 2012 in NATURE by scientists at Weill Cornell Medical College) discovered that a single protein (alpha 2 delta), “…exerts a spigot-like function controlling the volume of neurotransmitters and other chemicals that flow between the synapses of brain neurons.” This study shows how brain cells “talk to each other” through these synapses relaying feelings, thoughts, and actions and how this powerful protein plays a crucial role in regulating effective communication in the brain. They found that if they added or decreased this single protein (alpha 2 delta), then the speed of neurotransmission increased or decreased by opening or closing the calcium channels that trigger neurotransmission release.

The relationship between calcium and neurotransmission has been known for 50 years, but how to “turn on or off” the volume is a new discovery. They hope this finding will help in the design of new medications that will help regulate the neurotransmission in the brain, thus help reduce the increased pain perception found in people suffering from fibromyalgia.

Our aim in sharing this information with you is to keep you informed with what is on the cutting edge of research as we’ve said many times before, a “team” of health care provision is the BEST way to manage FM including chiropractic and primary care!

Dr. Stripling’s weekly video, Skiing / Snowboard / Snowshoe injuries & the 1-page health news from Denver Chiropractic Center

After spending time with our families this (past) holiday season, those of us who make up the staff of Denver Chiropractic Center (Dr. Hyman, Dr. Stripling, Miss Keri, and Awesome Massage Therapist Erin are back in the office on January 2 at 10AM and ready to help you. It’s going to be a great 2013!

We (Glenn & my wife Meredith) took the kids skiing / snowboarding / snowshoeing, and this season’s snow is looking great. That probably means that some of you are feeling the inevitable aches and pains that come with winter sports. Don’t let pain slow you down, give us a call.

Dr. Stripling and Miss Keri returned from Iowa (gee, I’ve never had employees spend so much time together) to post Dr. Stripling’s latest video for those of you who work at a desk- how to open those shoulders and improve your posture. See previous post for the video.

Here’s this week’s 1-page health news.

Mental Attitude: Anxious Parents? Parents diagnosed with social anxiety disorder are more likely to exhibit less warmth and affection towards their children, criticize them more, and express doubts about their child’s ability to complete a task. This can heighten anxiety in their child, and over time, can increase the chance their child will develop an advanced anxiety disorder of their own. Child Psychiatry and Human Development, November 2012

Health Alert: Parental Math Skills and Medication Errors. Parents with poor math skills (3rd grade level or below) are 5 times more likely to measure the wrong dose of medication for their child than parents with math skills at the 6th grade level or greater. In a study of 289 parents, 27% had math skills at 3rd grade level or below. American Academy of Pediatrics, April 2012

Diet: Processed Meat. Processed meat consumption increases the risk of prostate cancer. Processed red meat was associated with a 10% increased risk of prostate cancer with every 10 grams (about one-third of an ounce) of increased intake. This means stay away from the cheap stuff and spring for grass fed beef, available at Vitamin Cottage and Whole Foods. American Journal of Epidemiology, October 2009

Exercise: 5 Major Reasons. Exercise helps control your weight preventing excess weight gain or maintaining weight loss, combats health conditions and diseases, improves mood, boosts energy, and promotes better sleep. Mayo Clinic

Chiropractic: Spinal Degenerative Joint Disease and Pain. There are several reasons spinal degeneration causes pain: 1. Mechanical compression of nerve by bone, ligament, or the disk. 2. Biochemical mediators of inflammation.
3. Mechanical nerve compression results in decreased blood flow and swelling, which causes lack of proper motion leading to fibrotic tissue formation. Spine, 1989 In our opinion, nothing staves off spinal degeneration better than a healthy diet and regular treatment with Active Release and adjustments.

Wellness/Prevention: Get Your Sleep! Sleep disorders lead to 253 million days of sick leave a year in the United States. 63.2 billion dollars are lost a year due to insomnia. A third of this is due to absence from work, while the other two thirds is due to a loss in productivity at work. 10% of the population suffers from insomnia. Sleep apnea affects 4-5% of the population. University of Bergen, November 2012. Shoot for 7 hours a night, minimum.

Quote: “Those who think they have no time for bodily exercise will sooner or later have to find time for illness.”
~ Edward Stanley